ABCC8 gene in spinal cord
Team: University of Maryland
Journal of Translational Medicine Science
In spinal trauma, a mechanism to protect cells against an influx of intracellular calcium, sodium is returned to the inside Cell. This protection mechanism is overexpressed in trauma, in fact aggravate the damage related to trauma.
is the ABCC8 gene via the protein SUR1, which is at the origin. The blocking of this gene in mice and rats in the study showed a better functional recovery in the long term. Emergency treatment could be envisaged based on RNA interference, for example?
http://www.lesechos.fr/depeches/medecine-sante/afp_00246697.htm?xtor=RSS-2114
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